How to Assemble Genomes:
A step-by-step guide

Automated 3D Assembly

3D-DNA Source on Github

$1K Assemblies




Olga Dudchenko, Muhammad S. Shamim*, Sanjit Batra*, Neva C. Durand, Nathaniel T. Musial, Ragib Mostofa, Melanie Pham, Brian Glenn St Hilaire, Weijie Yao, Elena Stamenova, Marie Hoeger, Sarah K. Nyquist, Valeriya Korchina, Kelcie Pletch, Joseph P. Flanagan, Ania Tomaszewicz, Denise McAloose, Cynthia Pérez Estrada, Ben J. Novak, Arina D. Omer, Erez Lieberman Aiden.
The Juicebox Assembly Tools module facilitates de novo assembly of mammalian genomes with chromosome-length scaffolds for under $1000.
bioRxiv 2018.

Olga Dudchenko, Sanjit S. Batra*, Arina D. Omer*, Sarah K. Nyquist, Marie Hoeger, Neva C. Durand, Muhammad S. Shamim, Ido Machol, Eric S. Lander, Aviva Presser Aiden, Erez Lieberman Aiden.
De novo assembly of the Aedes aegypti genome using Hi-C yields chromosome-length scaffolds.
Science 2017.

Let's Get In Touch!

We're looking for great scientists and postdocs to join our team, especially computer scientists, biophysicists, and molecular biologists. But if you're a really creative scientist of any variety and are interested in the sorts of things we do, reach out to us! You will have the opportunity to work on a broad array of projects with an interdisciplinary approach. Applied and theoretical aspects of computer science, mathematics, physics, biology, engineering, and economics are used to make landmark discoveries in our lab. If you're interested in joining or collaborating on projects, reach out to us!